Histopathological changes caused by noise exposure in lung, heart, kidney, and liver tissues in New Zealand white rabbits
Abstract
Introduction: Noise exposure is a common phenomenon in all personal life activities. Due to the prevalence of exposure to noise, many people are exposed to noise. Some of the harmful effects of noise on human health
have been proven so far. The purpose of this study was to experiment histopathological effects caused by exposure to white noise.
Materials and methods: Four New Zealand white rabbits were exposed to 85±2 dB white noise for five consequent days. Heart, kidney, liver, and lung tissues were studied by the Hematoxylin and Eosin staining (H&E) method. The independent t-test was used for comparing the mean weight of tissues.
Results: This study showed that exposure to 85±2 dB white noise did not significantly change heart and lungs tissues. Nevertheless, this study indicated that exposure to noise induced different pathological changes
in kidney and liver tissues. Exposure to noise made congestion, unclear brush border, and tubular cell vacuolization in kidney tissue. Moreover, eosinophilic cytoplasm was made by noise exposure in liver tissue. Furthermore, no statistically significant difference was detected in the mean tissue weight/mean body weight in rabbits.
Conclusion: This study showed that exposure to noise might be a risk factor for different renal and hepatic diseases. Nevertheless, more studies need to complete these results.
Kazemi T, Mesgari-Abbasi M. Inflammatory
and immunological changes caused by noise
exposure: A systematic review. Journal of
Environmental Science and Health, Part C.
2020 Jan 2;38(1):61-90.
2. Rompel S, Schneider A, Peters A, Kraus U,
INGER Study Group. Sex/gender-differences
in the health effects of environmental noise exposure on hypertension and ischemic heart
disease—a systematic review. International
journal of environmental research and public
health. 2021 Jan;18(18):9856.
3. Pretzsch A, Seidler A, Hegewald J. Health
effects of occupational noise. Current
pollution reports. 2021;7(3):344-358.
4. Khan J, Ketzel M, Kakosimos K, Sørensen
M, Jensen SS. Road traffic air and noise
pollution exposure assessment–a review of
tools and techniques. Science of the total
environment. 2018 Sep 1;634:661-76.
5. Singh N, Davar SC. Noise pollutionsources, effects and control. Journal of
human ecology. 2004;16(3):181-187.
6. Zannin PH, Diniz FB, Barbosa WA.
Environmental noise pollution in the city
of Curitiba, Brazil. Applied acoustics.
2002;63(4):351-358.
7. Ma KW, Mak CM, Wong HM. The
perceptual and behavioral influence
on dental professionals from the noise
in their workplace. Applied acoustics.
2020;161:107164.
8. Golmohammadi R, Darvishi E, Motlagh
MS, Faradmal J, Aliabadi M, Rodrigues MA.
Prediction of occupational exposure limits
for noise-induced non-auditory effects.
Applied ergonomics. 2022 Feb 1;99:103641.
9. Basner M, Babisch W, Davis A, Brink M,
Clark C, Janssen S, Stansfeld S. Auditory
and non-auditory effects of noise on health.
The lancet. 2014 Apr 12;383(9925):1325-32.
10. Forsyth RP. Mechanisms of the
cardiovascular responses to environmental
stressors. Cardiovascular psychophysiology.
2017:5-32.
11. Kostić J, Kolarević S, Kračun-Kolarević
M, Kostić J, Kolarević S, Kračun-Kolarević
M, Aborgiba M, Gačić Z, Paunović M,
et al. The impact of multiple stressors on
the biomarkers response in gills and liver
of freshwater breams during different
seasons. Science of the total environment.
2017;601:1670-1681.
12. Bandoli G, von Ehrenstein O, Ghosh JK,
Ritz Bl. Synergistic effects of air pollution
and psychosocial stressors on adolescent
lung function. Journal of allergy and clinical
immunology. 2016;138(3):918-920.
13. Figueredo VM. The time has come
for physicians to take notice: the impact
of psychosocial stressors on the heart.
The American journal of medicine.
2009;122(8):704-712.
14. Tamer MM AA, Wagih M AH, Ayman F
ES, Lotfy S M, Salah E M, Abdel Ghany H
AG, Neama M T. Effect of crowding stress
on lung and heart of the adult albino rats
and the possible protective role of sulpiride.
The Egyptian journal of hospital medicine.
2014;57(1):580-597.
15. Oliveira MJ, Freitas D, Carvalho AP,
Guimarães L, Pinto A, Águas AP. Exposure
to industrial wideband noise increases
connective tissue in the rat liver. 2012.
16. Xue L, Zhang D, Wang T, Shou X. Effects
of high frequency noise on female rat's
multi-organ histology. Noise health. 2014
Jul-Aug;16(71):213-7.
17. Zymantiene J, Zelvyte R, Pampariene I,
Aniuliene A, Juodziukyniene N, Kantautaite
J, et al. Effects of long-term construction
noise on health of adult female Wistar rats.
Polish journal of veterinary sciences. 2017.
18. Abouee-Mehrizi A, Rasoulzadeh Y,
Mesgari-Abbasi M, Mehdipour A, EbrahimiKalan A. Nephrotoxic effects caused by
co-exposure to noise and toluene in New
Zealand white rabbits: A biochemical and
histopathological study. Life sciences.
2020;259:118254.
19. Abouee-Mehrizi A, Rasoulzadeh Y,
Mehdipour A, Alihemmati A, Rahimi E.
Hepatotoxic effects caused by simultaneous
exposure to noise and toluene in New Zealand white rabbits: a biochemical and
histopathological study. Ecotoxicology.
2021;30(1):154-163.
20. Cobo P, Murillo-Cuesta S, Cediel R,
Moreno A, Lorenzo-García P, Varela-Nieto
I. Design of a reverberant chamber for noise
exposure experiments with small animals.
Applied acoustics. 2009;70(8):1034-1040.
21. Oliveira MJ, Freitas D, Carvalho AP,
Guimarães L, Pinto A, Águas AP. Exposure
to industrial wideband noise increases
connective tissue in the rat liver. Noise and
health. 2012;14(60):227.
22. Xue L, Zhang D, Wang T, Shou X.
Effects of high frequency noise on female
rat's multi-organ histology. Noise and health.
2014;16(71):213.
23. Gannouni N, Mhamdi A, El May M,
Tebourbi O, Rhouma KB. Morphological
changes of adrenal gland and heart tissue
after varying duration of noise exposure in
adult rat. Noise and Health. 2014;16(73):416.
Files | ||
Issue | Vol 6 No 4 (2021): Autumn 2021 | |
Section | Original Research | |
DOI | https://doi.org/10.18502/japh.v6i4.8584 | |
Keywords | ||
Noise; Environmental exposure; Occupational exposure; Toxicology; Histopathology |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |