Tehran University of Medical Sciences Journal of Air Pollution and Health 2476-3071 1 3 2016 09 04 219 226 EN Morteza Khafaie Environmental Technologies Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AND Department of Public Health, Faculty of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Ajay Ojha Technogreen Environmental Solutions, Pune, Maharashtra, India Sundeep S. Salvi Chest Research Foundation (CRF), Pune, Maharashtra, India Chittaranjan S. Yajnik King Edward Memorial Hospital Research Center, Pune, Maharashtra, India 2016 06 18 2016 08 21 Number of scientific studies linking possible effects of air pollution on health are increasing. However, the disparity in the effect estimated from different studies and recognizing important determinants of these diversity are essential . We have explained the types and sources of air pollution, and the common terms in epidemiological studies of air pollution. Then we reviewed the study design and critically evaluated methodological approach to estimate association between air pollution and health with deep insight into dispersion model. The quality of exposure measurement is critical determinant in an environmental epidemiology study. However, the available exposure data and feasible methods for its collection are often the determinant of the design to be used. Beside vast development in this field, epidemiological approaches to find out the risks of exposure to air pollutants is still challenging. https://japh.tums.ac.ir/index.php/japh/article/view/50 https://japh.tums.ac.ir/index.php/japh/article/download/50/32